Christine Brennan appeared on Coronation Street in six roles:
- Dawn Watson, a work colleague of Alan McKenna in March 1997
- Doctor Neville, who was on duty when Judy Mallett gave birth to twins William and Rebecca in December 1998
- PC Jones who, along with colleague PC Harper, arrested Curly Watts in Coronation Street as he staggered home drunk from his stag night celebrations in December 2000
- Housing officer Belinda Sawyer, who in October 2002 investigated whether Kirk Sutherland was a sub-letting tenant at No.5
- An unnamed Doctor in July and September 2012
- Fostering agent Trudy Michaelson who met with Brian Packham and Julie Carp in November 2013.
Her other credits include roles in Children's Ward, A Touch of Frost, Emmerdale and the TV movie The Girls Who Came to Stay. On stage she appeared in a September 2001 production of Black Love at the Cochrane Theatre, London.