Christine Mackie has appeared in four different roles on Coronation Street:
- A Nurse based at Blackpool's Victoria Hospital where Rita Fairclough was briefly admitted in December 1989.
- Chris Jones between April and May 1992.
- Salsa dancing instructor Bella in May 2010.
- Dr Gaddas intermittently from August 2014 to July 2016.
Her other credits include roles in French and Saunders, Children's Ward, Heartbeat, All Quiet on the Preston Front, Peak Practice, The Bill, Wire in the Blood, Casualty, Fat Friends, The Royal, Doctors, Hollyoaks, Holby City, My Phone Genie and Downton Abbey.